B cell memory: building two walls of protection against pathogens
… depend on their ability to induce B cell memory, we have not yet succeeded in … necessary
to further elucidate the mechanisms that drive the differentiation of these memory B cell subsets…
to further elucidate the mechanisms that drive the differentiation of these memory B cell subsets…
Double-negative (DN) B cells: an under-recognized effector memory B cell subset in autoimmunity
Y Li, Z Li, F Hu - Clinical & Experimental Immunology, 2021 - academic.oup.com
… B cell subset may play an important role in the pathogenesis and progression of diseases,
functioning as effector cells. Their alterations and roles in disease are summarized in Table 3. …
functioning as effector cells. Their alterations and roles in disease are summarized in Table 3. …
Comprehensive analyses of B-cell compartments across the human body reveal novel subsets and a gut-resident memory phenotype
NM Weisel, FJ Weisel, DL Farber… - Blood, The Journal …, 2020 - ashpublications.org
… such B-cell lineages in tissues relate to blood is needed, and … The current study addresses
this need by using a unique … novel MBC subsets, including a tissue-resident subset in the …
this need by using a unique … novel MBC subsets, including a tissue-resident subset in the …
Failed B cell survival factor trials support the importance of memory B cells in multiple sclerosis
… Recent successes with CD20-depleting antibodies have focused attention towards B cell
subsets as important mediators in MS. The trial of tabalumab (NTC00882999), which inhibits …
subsets as important mediators in MS. The trial of tabalumab (NTC00882999), which inhibits …
Memory B cells and plasma cells: The differentiative continuum of humoral immunity
MP Cancro, MM Tomayko - Immunological reviews, 2021 - Wiley Online Library
… establish heterogeneity in memory B cell phenotype, function, … CD80/PD-L2/CD73 memory
B cell subsets were initially … features or constituents are required for MBC survival, such …
B cell subsets were initially … features or constituents are required for MBC survival, such …
[HTML][HTML] Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass …
E Blanco, M Pérez-Andrés, S Arriba-Méndez… - Journal of Allergy and …, 2019 - Elsevier
… to the limited number of B-cell populations investigated, the lack of appropriate age-matched …
of blood B-cell subsets throughout life, 24 most reports on B-cell compartments in patients …
of blood B-cell subsets throughout life, 24 most reports on B-cell compartments in patients …
Naive-and memory-like CD21low B cell subsets share core phenotypic and signaling characteristics in systemic autoimmune disorders
M Freudenhammer, RE Voll, SC Binder… - The Journal of …, 2020 - journals.aai.org
… low B cell subsets in one single patient. (E–G) Mean values of the proportions of naive-like,
IgM memory, CD27 + switched memory, and CD27 − switched memory B cell populations in …
IgM memory, CD27 + switched memory, and CD27 − switched memory B cell populations in …
The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets
T Koike, K Harada, S Horiuchi, D Kitamura - Elife, 2019 - elifesciences.org
… can be B-cell-intrinsic and essentially independent of B-cell … enough to recapitulate the
distinct B cell fate decisions in an in … We next sought to clarify a need for GC in the development …
distinct B cell fate decisions in an in … We next sought to clarify a need for GC in the development …
Challenges and opportunities for consistent classification of human B cell and plasma cell populations
I Sanz, C Wei, SA Jenks, KS Cashman… - Frontiers in …, 2019 - frontiersin.org
… of the major canonical human B cell subsets can be achieved … four distinct B cell fractions:
(I) switched memory (SM) B cells … Additionally, we raise the need for awareness that not all …
(I) switched memory (SM) B cells … Additionally, we raise the need for awareness that not all …
[HTML][HTML] Remembrance of things past: long-term B cell memory after infection and vaccination
AKE Palm, C Henry - Frontiers in immunology, 2019 - frontiersin.org
… with memory B cell generation, but further studies are needed … A great variety of B cell
subsets have been identified in the … of development of a naive B cell into a memory B cell. In the …
subsets have been identified in the … of development of a naive B cell into a memory B cell. In the …
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